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However, emerging evidence suggests there may also be a direct metabolic effect on cartilage cells, helping them produce energy more efficiently and potentially supporting tissue survival and repair
In line with the concept that T cell activation and differentiation require metabolic adaptation, SLC1A5 couples TCR and CD28 signals to ultimately activate the mTORC1 pathway and enable the cell to undergo clonal expansion (105)
Science 336, 10401044
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