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Depletion of PAPS due to lack of inorganic sulfate or due to genetic defects of enzymes participating in PAPS synthesis may lead to reducing of sulfonation capacity which could affect the metabolism of xenobiotics or disrupt the equilibrium between synthesis and degradation of active endogenous compounds
It works by blocking androgen receptors and reducing sebum production
J Biol Chem 290(47):2809728106
Daryabor, G., Atashzar, M.R., Kabelitz, D., Meri, S
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