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Moreover, when mice were pre-treated with vehicle or L2-Cmu (20 mg/kg) by intraperitoneal (i.p.) injection, and then challenged with an intravenous (i.v.) bolus of saline or 5 g IGF-1, L2-Cmu was able to modulate IGF-1R activation in vivo, as demonstrated by a near complete inhibition of IGF-1R phosphorylation in lung and ~70% inhibition in heart (Fig
Published 2022 Oct 12
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FIGURE 5 Discussion In this study, bidirectional and unidirectional MR analyses were conducted to assess the causal relationship between endogenous and exogenous antioxidants and the six types of cancer
Effects of Selenium Supplementation on Graves Disease: A Systematic Review and Meta-Analysis
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