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It is notable that the absolute value of the HR was in fact similar to that in the SUSTAIN-6 trial

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Without medical supervision and regular monitoring, altering your dosing schedule also makes it harder to identify which dose level actually triggered an adverse effect or achieved your weight loss plateau

When it comes to weight management, the journey can often feel overwhelming, especially with the myriad of fad diets and quick fixes that promise rapid results but rarely deliver lasting success

NICE (CG189) additionally recommends framing goals in terms of overall outcomes for example, a 510% reduction in body weight over three to six months within a multi-component programme which can be more motivating and clinically meaningful than focusing solely on weekly targets