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The Wegovy pill dosing schedule is: Day 1 - 30 (Starting dose) - 1.5mg tablet once a day for 30 days Days 31 - 60 - 4mg tablet once daily for 30 days Days 61 - 90 - 9mg tablet once daily for 30 days Days 91 onwards (maximum dose) - 25mg once a day

METs decreased when macrophages were subjected to MSC-sEVs(Fig), and when METs were co-cultured with hepatocytes, apoptosis increased and proliferation decreased, which were reversed by the inhibition of METs

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For weight loss, the NHS offers a similar medication, Wegovy , but under strict eligibility criteria