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The substance demonstrates potential as a new treatment target because it has both anti-inflammatory properties and the ability to protect cartilage from damage
Range: 0 - 100ng/ml Average IC50: 3.45ng/ml Immunogen: Synthetic peptide H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val[1]Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys[(AEEA)2--Glu-N-(17- carboxy-1-oxoheptadecyl)]-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly[1]Arg-Gly-OH coupled to carrier protein
Of note, TGF- also activates DA signalling to promote reproduction at the dauer checkpoint (Fielenbach and Antebi, 2008)
However, its important to note that compounded versions arent FDA-approved
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