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In the absence of Keap1, Nrf2 is constitutively stabilized, and the expression of Nrf2 target genes is maintained at high levels (Wakabayashi et al., 2003)
By working through the nasal mucosa, the therapy provides rapid absorption and a more direct route to the bloodstream than oral options
The muscle of the leg between the knee and the hip (your lap) is fine, as is the upper outer quadrant of the buttock
Protects gastric and intestinal tissue through upregulation of cytoprotective factors including heme oxygenase-1 and heat shock proteins
& Zhou, L
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