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2016;6(2):e009389
The documented pattern is simply a steady daily presence of the inhibitor, held long enough for the downstream metabolic change to accumulate
doi: 10.1152/ajpendo.00347.2016 174 AsmarMAsmarASimonsenLGasbjergLSSparre-UlrichAHRosenkildeMMet al
They complement each other by improving skin brightness, strengthening the barrier, and reducing pigmentation
However, this process also creates inflammation and oxidative byproducts
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