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1 5 Overcoming Metabolic Adaptation: During significant weight loss, the body can enter a state called metabolic adaptation , where it becomes more energy-efficient and burns fewer calories, often leading to a plateau

This is because Vitamin B12 is involved in synthesizing serotonin, a neurotransmitter responsible for regulating mood

This improves athletic performance

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Furthermore, it has been reported that fatigue induced by progressive disease is often coupled with weight loss and anorexia [24]