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Therefore, to safely harness the attractive catabolic and thermogenic effects of glucagon for treating metabolic disease, a counter-balancing therapy that selectively opposes the risk for glucagon-induced hyperglycaemia is required
Liu, Z., et al
In preclinical research, CJC-1295 has demonstrated the ability to stimulate growth hormone secretion through the GHRH receptor pathway while maintaining the pulsatile release pattern that characterizes physiological growth hormone regulation
Data availability All data used to build and validate models in addition to all peptide sequences designed and tested in this study are freely available for download from the code repository at Source data are provided with this paper
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