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Concomitant use of G-Omeprazole 40 mg/vial (and PPIs in general) with methotrexate particularly at high doses may elevate methotrexate and hydroxymethotrexate plasma levels, increasing the risk of methotrexate toxicity
This biphasic dose-response curve means higher concentrations do not produce proportionally greater anti-inflammatory effects and may reverse therapeutic benefits
Thank you again I've never seen B12 listed as a cure for eczema but if it wasn't what cured her skin issues it was awfully coincidental
doi: 10.1007/BF00399926
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