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E1 is a thiamin pyrophosphate (TPP)-dependent -ketoacid dehydrogenase, R -lipoic acid functions as a prosthetic group essential for E2 transacetylase activity, and E3 is a flavin adenine dinucleotide (FAD)-dependent dihydrolipoamide dehydrogenase ( Figure 4 )
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Research by Antony (2003, American Journal of Clinical Nutrition) documented B12 deficiency in 47 to 74 percent of Indian vegetarians
Complex CCM Codes (99487, 99489) These codes apply to more advanced care management services involving moderate or high-complexity medical decision-making
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