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Additionally, during the acridine orange (AO) reaction for a lysosome membrane permeability assay, the cells with indicated treatments were stained with 2 g/mL AO (Invitrogen) for 15 min at 37 C
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Approximately 70% of high-dose participants achieved 5% weight loss, with 48% reaching 10% reduction (Gadde et al., Lancet, 2011)
These studies could provide valuable insights into how BPC 157 can be used to manage and potentially treat this debilitating disease
Angew Chem Int Ed 61:16
