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doi: 10.1016/j.phrs.2019.104554 12 TalenezhadNMohammadiMRamezani-JolfaieNMozaffari-KhosraviHSalehi-AbargoueiA

[1] [3] According to its Summary of Product Characteristics (SmPC), it is indicated to improve glycaemic control in adults when diet and exercise alone prove insufficient, either as monotherapy when metformin is inappropriate or as an add-on therapy with other diabetes medications

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NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 [PMID: 26928119] Laboratory literature summary: NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4(+) CD25(+) Foxp3(+) T cells