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One of the central regulatory pathway in redox balance is the Kelch-like ECH-Associating protein 1 (Keap1)nuclear factor erythroid 2 related factor 2 (Nrf2)antioxidant response element (ARE) pathway, which upregulates biosynthesis of antioxidant proteins, including antioxidant enzymes such as heme oxygenase-1 (HO-1), glutathione S -transferase, NAD(P)H:quinone oxidoreductase 1 (NQO1), glutathione reductase (GR), Trx-R, CAT, and SOD, but also nonenzymatic antioxidant proteins, e.g., Trx or anti-apoptotic proteins from Bcl-2 family 64
Adding or maintaining lean mass can nudge your resting calorie needs upward over time, which can help with weight loss
SHR, Spontaneously hypertensive rat
Purity quantified via High-Performance Liquid Chromatography (HPLC) and identity confirmed by Liquid Chromatography-Mass Spectrometry (LC-MS)
British Journal of Pharmacology / NIHMS PMC (2008) 6
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