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Notably, lactate-induced ALDH2-K52la in renal cells disrupts its interaction with PHB2, a critical mitophagy receptor, leading to PHB2 degradation, impaired mitophagy, and worsened kidney damage

& Goggins, M

Although NE is present in the intestinal lumen 24 , it is not clear whether NE in the intestinal tissue is released into the intestinal lumen and there appear to be no reports of NE-mediated increases in E