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Ratio values were used due to different expression levels of the GFP-constructs among the cell population

When copper handling is impaired, reactive copper may increase oxidative stress and place greater demand on glutathione and other antioxidant defenses

Xenobiotic-Induced Oxidative Stress & Cellular Signaling Reactive oxygen and nitrogen species generated by xenobiotic metabolism can cause DNA damage, protein oxidation, and lipid peroxidation if not adequately regulated

PMID: 41026812 Dev Cell A single fluorescent probe to examine the dynamics of mitochondria-lysosome interplay and extracellular vesicle role in ferroptosis