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The use of wholesale acquisition costs for the drug costs may not be reflective of the costs ultimately borne by the healthcare payer due to privately negotiated discounts, manufacturer rebates, or patient co-pay to offset the cost of the drug
Methods We followed the Preferred Reporting Items of Systematic Reviews and Meta-Analysis ( PRISMA ) statement guidelines to report this review [14]
Corticosteroids, particularly when used at moderate to high doses or for prolonged periods, can cause significant metabolic effects that may counteract weight loss efforts
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