No one knows for sure, but evidence supports the theory that the increase in free radicals and the resulting oxidative damage is partially to blame
Collagen supplementation in metabolic syndrome: a narrative review unraveling the biological mechanisms and effects Published online by Cambridge University Press: 22 December 2025 Abstract Collagen supplementation (CS) has emerged as a promising therapeutic approach with potential benefits for managing metabolic syndrome (MetS)-related risk factors
In fact, a study reported that 16.9-35.3% of IBS-D patients had been diagnosed with BAM (Slattery et al., 2015)
Early clinical trials have shown promising results, with agents like semaglutide and exenatide demonstrating reductions in alcohol consumption and craving, as well as potential benefits for smoking cessation, such as reduced post-cessation weight gain
That means it is prohibited for tested athletes at all times, both in and out of competition, with no therapeutic-use exemption, and the ban is still in force on the 2026 list