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So, they are available for use by the body immediately

15 In the SURPASS-1 study, tirzepatide monotherapy at increasing doses of 5, 10, and 15 mg resulted in significant weight loss of 7, 7.8, and 9.5 kg, respectively, at week 40 in patients with T2DM, compared with a 0.7 kg decrease with placebo

The evidence: no published study has shown tirzepatide or semaglutide directly binding to or antagonizing reproductive hormone receptors

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- Red flag: dose escalations require extra "consultation fees" beyond the base subscription