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Kavukcu, S., Turkmen, M., Salman, S., Onvural, B., Oktay, G., Karaman, O., and Cevik, N
Semaglutide is an FDA-approved GLP-1 receptor agonist, originally used to treat type 2 diabetes and now widely recognized for its ability to reduce appetite and promote weight loss (marketed as Wegovy and Ozempic)
The similarities indicate that patients with HD may undergo similar changes in glutathione metabolism during the asymptomatic stage owing to the loss of BDNF-TrkB signalling, leading to striatal vulnerability
Dimethyl fumarate increased the activities of SOD, Gpx, CAT, and levels of total thiol (Figure 2)
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