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During the process, influx of glucose ensures sufficient ATP to sustain the stimulatory effect
Lin WS, et al
Three major GLP-1 trials came out in late 2025
The American Diabetes Association recommends monitoring HbA1c every 3 months during dose titration, with assessment of weight, blood pressure, and medication tolerance at each visit
Under oxidative stress, accumulation of ROS can activate pathways such as the JNK and the p53, further inducing autophagy, which helps clear damaged organelles, reduces oxidative damage, and protects cell survival [256]
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