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It is believed that correcting aging hallmarks could help people age in a healthier way, Sekhar said

Add GIP and glucagon receptor activation on top of that, and you have three separate pathways all affecting digestion simultaneously

doi: 10.3389/fphar.2025.1567863 Received 28 January 2025 Accepted 21 April 2025 Published 01 May 2025 Volume 16 - 2025 Edited by Miguel Oliveira, University of Aveiro, Portugal Reviewed by Yuling Han, Chinese Academy of Sciences (CAS), China Gary Ten Eyck, New York University, United States Satish Polshettiwar, MIT World Peace University, India Updates Copyright 2025 Feng, Qu and Hao

Learning Objectives Determine the prevalence and impact of obesity on health and the role GLP-1 medications play in managing obesity and obesity-related conditions, including their mechanisms of action and effects on patient care Distinguish the specific challenges that GLP-1 medications present in rehabilitation, including their side effects, such as caloric deficit, gastrointestinal issues, loss of muscle mass, challenges of medication discontinuation, glycemic control, and weight regain, and how these factors affect patient management Implement effective management strategies for rehab professionals working with patients on GLP-1 medications, encompassing comprehensive screening and intervention strategies, identification and management of red flags, and approaches to mitigate incomplete medication histories Construct personalized treatment plans that consider the importance of muscle mass preservation through resistance training, appropriate protein and nutrient intake, and the implementation of lifestyle behavior modifications using principles of behavior change Examine the interdisciplinary collaboration opportunities to enhance patient care and support, ensuring rehab professionals can effectively contribute to a holistic healthcare approach for patients using GLP-1 medications Analyze the current research and considerations around the effects of GLP-1 medications and implications for rehabilitation practices Meet your instructors Anna DeLaRosby Anna has been a physical therapist since receiving her doctorate in physical therapy in 2008 and loves all things PT

Causes: Allopurinol, phenytoin, isoniazid, quinine, penicillin, quinidine Vascular lesions: They result from injury to the vascular endothelium