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Mar 15 2012;131(2):387-396
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The first major breakthrough in this domain was the development of split-fluorescence contact sensors, most notably the split-GFP-based contact site sensor (SPLICS)
Increased esterification of fatty acid by liver is associated with higher secretion of triglyceride into the circulation as VLDL
Without this data, making informed dose adjustments becomes guesswork
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