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AAS and ESAs exhibit the strongest ergogenic signals but are also associated with myocardial remodeling, arrhythmia, and thrombotic events
Establishing a daily routine that incorporates balanced meals, sufficient hydration, and physical activity will help minimize discomfort
Replacement of Tyr110 in recombinant Y110A decreased both k cat app and 1/ values for the disulfide substrate and GSH in the GSSCys and HEDS assay (Supplementary Figs 18 and 19)
Phase 3 trials with larger populations and longer follow-up periods will be essential to characterise the safety profile more comprehensively
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