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Semaglutide and Hormone Replacement Therapy If you Google Semaglutide and HRT as a combo of therapies, you will find studies showing evidence of how the two together can substantially impact weight loss during our perimenopause and menopause years

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GLP-1 plays several critical roles in glucose and appetite regulation: it stimulates insulin release from the pancreas, inhibits glucagon secretion to prevent excess glucose production, slows gastric emptying to moderate post-meal blood sugar spikes, and promotes satiety by acting on hunger centers in the brain (6)(23)

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