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Soczynska JK, Mansur RB, Brietzke E et al (2012) Novel therapeutic targets in depression: minocycline as a candidate treatment

Journal of orthopaedic research : official publication of the Orthopaedic Research Society , 28 (9), 1155-61

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They started looking at what FOXO4 actually does in senescent cells, and one important thing was that it liked to grab on (bind) to a protein called p53