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Gastrointestinal Applications The peptides strong association with digestive system research has made it a cornerstone compound in studies involving intestinal tissues, mucosal barriers, and gastrointestinal integrity

Investigators also have hypothesized that cyclosporine can modify resistance to chemotherapy by augmenting the cytotoxic effect of drugs through inducing a GSH deficiency

Wakabayashi T, Yamaguchi K, Matsui K, Sano T, Kubota T, Hashimoto T, Mano A, Yamada K, Matsuo Y, Kubota N, Kadowaki T, Iwatsubo T (2019) Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimers disease

Effective doses spanned six orders of magnitude (10 pg/kg to 10 mcg/kg)

But that was only the beginning