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for Medicare Part C, a pre-determination of benefits is made

Upon exposure to danger signals, dendritic cells migrate to lymphoid organs and present antigens on MHC-I or MHC-II molecules to T and B lymphocytes as well as natural killer (NK) cells (72, 73) ( Figure 3A )

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This is most relevant for weight-based peptides like kisspeptin (dosed in mcg/kg) and less relevant for receptor-saturating peptides like BPC-157, where tissue concentration at the injury site matters more than total body distribution

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