Aged mice were intraperitoneally injected with 5 mg/kg FOXO4-DRI or PBS as a control every other day for three administrations, and effects were assessed 30 days post-treatment
Results from this study suggest that hepatic fat export in periparturient dairy cows is improved by choline supplementation during the transition period and this may potentially decrease the risk for metabolic disorders in the periparturient dairy cow.12 Choline is also known to be involved in the synthesis of carnitine, cell membrane phospholipids, and the neurotransmitter acetylcholine
Moore AR, Zhou W-L, Sirois CL, Belinsky GS, Zecevic N, Antic SD (2014) Connexin hemichannels contribute to spontaneous electrical activity in the human fetal cortex
Ongoing studies explore its influence on cellular communication pathways associated with nutrient utilization, energy balance, and metabolic adaptation
Common Models Cell-culture assays, rodent tissue-injury models, ex vivo matrix-remodeling systems