In addition, when used in combination with DOX at sublethal concentrations, a reduction in IC 50 is observed, representing an increase in the net antitumor activity of the drug ( in vitro , P2Et is cytotoxic both in resistant lines with the expression of Pgp + and in Pgp-lines in 2D and 3D cultures ( C
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It happens because the medication slows down how quickly food leaves the stomach
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