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People with substance use disorder keep using drugs or alcohol even though it causes problems in their life

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Arguments for cycling include theoretical concerns about receptor desensitization, practical cost considerations, and conservative caution given limited long-term human data

Presented for research literature review only Chung PM et al

Efficacy and safety of once-weekly semaglutide 1.0mg vs once-daily liraglutide 12mg as add-on to 13 oral antidiabetic drugs in subjects with type 2 diabetes (SUSTAIN 1.0)