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- Temperature monitoring revealed that tissue 3 mm from the probe took 2.5 minutes to reach 20C and did not reach 40C, potentially limiting therapeutic effect
Copper delivery through the skin has many potential applications and thus is widely studied, including the evaluation of the penetration ability of copper peptides 30 , biocompatibility of copper containing IUD 1 , the enhancement of skin absorption through copper-containing nanoparticles 10 and microneedle-mediated delivery 5
several of these proteins play a critical role in preventing CDKs
Based on these measurements, the size of dissolved nanoparticle samples were relatively stable even after six months, but aggregation or disintegration cannot be excluded due to the large PDI values
