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At subtoxic level, NAPQI is detoxified by conjugation with reduced glutathione (GSH), both non-enzymatically and in a reaction catalyzed by glutathione S-transferases
The aqueous matrix is compatible with typical laboratory glassware, elastomeric closures, and common dispensing hardware under standard research conditions
The intensity can range from mild preference changes to strong aversive reactions that make certain foods nearly intolerable
The New England Journal of Medicine, 389 (2), 107117
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