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Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase

Donisi, 2025

On the other side, another study of the same Authors showed that liraglutide 1.2 mg/day determined a significant decrease in VAT area measured by DXA, and at the same time a greater reduction in body weight and BMI compared to metformin 1000 mg BID [57]

Previous studies have indicated that gut microbiota-derived short-chain fatty acids (SCFAs), particularly butyrate, play a crucial role in enhancing mitochondrial efficiency and energy production [6]

An important example is insulin resistance: reduced glucose uptake in cancer patients compared with healthy controls during an euglycemic hyperinsulinemic glucose clamp has commonly been observed not only during 7, 8 but also before weight loss or malnutrition