Demand for such drugs is likely to continue to be strong in the future due to rising rates of obesity and interlinked chronic diseases
Fatigue may result from multiple factors including significant caloric deficit from appetite suppression, metabolic adaptation to weight loss, nutritional deficiencies, gastrointestinal side effects affecting food and fluid intake, and changes in blood glucose levels
Policy GLP-1s act on receptors in many parts of the body, some of which were still figuring out, says endocrinologist Anira Iqbal, MD
Affectionately called 'Lizzie, or Gilly' by diabetic patients and marketed as 'Byetta', exenatide was the first slow-release GLP-1 mimic to reach the market (Schuler, Shearin)
Fibroblasts obtained from ALS patients carrying the CHCHD10 mutation S59L display respiratory chain deficiency, ultrastructural alterations, and fragmentation of the mitochondrial network (Bannwarth et al., 2020)