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The prevalence of AUD in humans indirectly suggests that naturally evolved regulatory systems can become dysfunctional (due to genetic and/or environmental factors), removing the evolutionary "brake" on excessive or health-impairing alcohol intake

Occasional missed doses are not catastrophic, but consistent administration produces the best results

And now, depending on the vantage point, things are about to get much bigger

The protocols below represent current best practices synthesized from available studies and clinical experience

Adverse reactions increase with overdose, so do not administer more than necessary