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In a post hoc analysis from the PROactive trial, weight gain with pioglitazone, a TZD, which leads to weight gain with a redistribution from VAT to SCAT and improvements in insulin sensitivity 62,63 , was associated with improved CV outcomes (excluding heart failure) 64
Peak weight loss ~15.6% Price $45.00 GLP2-T Adds GIP receptor agonism on top of GLP-1 3050% greater weight loss than single-agonist GLP-1 at comparable dosing
Both have similar side effect profiles (GI issues primarily), but individual responses vary
Mistake 2: adjusting the dose because of timing changes Some people, thinking they are being careful, reduce their dose when injecting early or increase it when injecting late
Peptides are short chains of amino acids naturally produced in our body
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