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10.3748/wjg.v10.i7.1032 Summary Keywords BPC157, pharmacokinetics, absorption, distribution, metabolism, excretion, wounds Citation He L, Feng D, Guo H, Zhou Y, Li Z, Zhang K, Zhang W, Wang S, Wang Z, Hao Q, Zhang C, Gao Y, Gu J, Zhang Y, Li W and Li M (2022) Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs
However, the large molecular weight, strong hydrophilicity and easy enzymatic hydrolysis of AOD 9604 result in its low bioavailability and limit its clinical application.The rise of nanotechnology has brought revolutionary changes to drug delivery systems
Methods of administration for BPC-157 in research settings include subcutaneous, intramuscular, and oral forms
The c-Jun N-terminal kinase (JNK) pathway is activated in human interstitial cystitis (IC) and rat protamine sulfate induced cystitis