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During OA, synovial tissue exhibits an inflammatory response, releasing IL-1, IL-6, TNF-, and other cytokines and chemokines that attract peripheral immune cells such as macrophages, neutrophils, and T cells to the synovial membrane (145, 146)
No receptor downregulation: Unlike some fat burners that lose effectiveness as your body adapts, AOD 9604 doesn't cause significant receptor desensitization
doi: 10.12890/2020_001646 53 PolonikovA
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