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Sharpe et al
Instead, it acts locally and degrades quickly
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In addition to being a therapeutic target, oxidative stress has been shown to decrease the GSH:GSSG ratio which has proven useful as a clinically accessible, pharmacodynamic biomarker of immune redox tone for conditions such as malignancy (Zitka et al., 2012)
Gold nanoparticles show a protective effect on DKD by targeting miR-192 and miR-21 to suppress TECs apoptosis (127)
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