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The SELECT trial demonstrated a 20% reduction in major adverse cardiovascular events (heart attack, stroke, cardiovascular death) in people with obesity and established cardiovascular disease
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Both drugs were well tolerated: overall less than 10% of patients discontinued treatment due to the occurrence of side effects, with no significant differences between the two formulations, despite a slightly higher discontinuation rate in oral semaglutide group
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Sassolas B, Haddad C, Mockenhaupt M, Dunant A, Liss Y, Bork K, et al
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