Consequently, other strategies for oral administration have been tested and developed, including (but not limited to) coadministration with enzyme inhibitors, structural modifications [cyclization, PEGylation, fatty acid conjugates of polypeptides (lipidization), fusing therapeutic proteins to cobalamin (vitamin B 12 )], and the use of delivery carriers or absorption enhancers
And yes, I did inject this stuff into my body
Lyophilised powder contains minimal water, which limits hydrolysisthe water-mediated breakdown of peptide bonds
In the 1990s, researchers discovered that Gila monster saliva contains a peptide called exendin-4, which acts like GLP-1 but resists enzymatic breakdown
On a U-100 graduated syringe, 100 units equals 1 mL, so a single unit equals 0.01 mL