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Pregnancy and lactation represent additional contraindications due to the absence of safety data in these populations

For type 2 diabetes (NG28), treatment should continue only if there is adequate response (11 mmol/mol [1.0%] HbA1c reduction and 3% weight loss at 6 months)

Early gestational diabetes is associated with worse pregnancy outcomes compared to women diagnosed with late gestational diabetes (hyperglycaemia typically from 24 weeks to 28 weeks of gestation)