Additionally, OCT-A can reveal diabetic macular ischemia (which appears clinically as areas of capillary nonperfusion), enlargement of the foveal avascular zone, and choriocapillary flow impairment
The most commonly reported adverse effects in clinical trials are gastrointestinal in nature, particularly during dose escalation
This variant is associated with reduced efficiency in glutathione production through the GCLC enzyme
Medvidovic-Grubisic M, Stambolija V, Kolenc D, Katancic J, Murselovic T, Plestina-Borjan I, et al
Magnetic resonance spectroscopy (MRS) allows the insight into their pathophysiology through exploration of a range of biochemicals putatively relevant to aetiological processes, in particular mitochondrial dysfunction and energy metabolism