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All experiments were performed as independent biological triplicates

Without resistance training, up to 40 percent of weight lost comes from lean mass, including muscle

Though patients may lose some muscle when they drop lean mass, it may be less than people think, says Randy Seeley, an obesity researcher at University of Michigan Medical School in Ann Arbor who was not involved with the study

Informed consent was obtained and the use of a patient specimen and relevant database was approved by the Human Research Ethics Committee of Tianjin Medical University

The intensity, timing, and type of exercise may need adjustment, particularly during the first few weeks of treatment or when your dose increases