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While the clinical impact varies, it is important to consider timing and dosing adjustments

Measures of body composition after GLP-1 use show a 2050% loss of lean mass

Nonetheless, the effectiveness, safety, and advantages of prolonged metformin use during pregnancy in patients with PCOS remain a topic of significant debate in the medical field

Genetic variation in GLP-1 receptor sensitivity, gut microbiome composition, and baseline metabolic status all play roles that are not yet fully understood

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