Our view: Oral GLP-1 supplementation, combined with good nutrition and consistent habits, is the more evidence-supported non-prescription option
In 2025, a joint advisory from four major organizationsthe American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Societypublished comprehensive nutritional guidelines for GLP-1 therapy (Mozaffarian et al., 2025)
Common Side Effects Nausea : Your stomach might feel queasy, especially when you first start
Lilly's oral GLP-1 drug, Foundayo (orforglipron), recently received FDA approval for obesity in adults and launched in April 2026
Triple GLP-1/GIP/glucagon agonist