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Short-acting RAs, such as exenatide (Byetta), lixisenatide and beinaglutide, have a duration of action of only a few hours after being subcutaneously injected., thus need multiple times injection daily

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Adipose tissue, especially visceral fat around the abdominal organs, is biologically active

And people with larger bodies will be blamed if they fail again to defy biology and keep the weight off, said Tigress Osborn, board chair of the National Association to Advance Fat Acceptance

At the same time, due to their long duration of action, the frequency of injections was reduced