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Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence

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Synthesis of pheomelanin starts with the conjugation of L-dopaquinone formed from L-tyrosine with cysteine

doi:10.1002/ana.22229

Oxidative stress induces the dissociation of the NRF2-Keap1 complex When cells undergo oxidative stress, ionizing radiation, or chemical stimulation, it may lead to the generation of reactive oxygen species (ROS) or reactive oxygen free radicals within the cells, triggering an oxidative stress response